Philadelphia coach Brett Brown wore a pre-game shirt designed by Australian guard Patty Mills, but it didn't bring him any luck as Toronto scored a tiebreaking basket with 4.9 seconds remaining on Wednesday.

The Raptors took full advantage of Philadelphia's missing stars, including two-time NBA All-Star Ben Simmons, to post a 125-121 win.

Simmons was absent because of a knee injury but it was another Australian - San Antonio Spurs guard Mills - on 76ers coach Brown's mind.

Brown said the shirt he wore before the game, featuring a white figure with his arm around a Black one, was designed by Mills whose mother was an Aboriginal and part of the "stolen generation."

He said the shirt represented "a cleansing of their version of Black children being brought into white suburban Adelaide".

"And so this American thing that we're going through with George Floyd and the flash points that we've all experienced here in the United States, it's not unique to this nation," added Brown.

Stanley Johnson scored the tiebreaking basket in the lane with time running out to give assistant coach Adrian Griffin his first NBA win.

Raptors coach Nick Nurse let his assistant run the team and they responded with a late run from the bottom of their bench, long after Philadelphia's Joel Embiid had ended his night, to improve to 6-1 in the restart.

Kyle Lowry and Chris Boucher each scored 19 points for the Raptors.

Embiid played just the first half after missing a game with a left ankle injury. He also took a hit on the hand and finished with five points in 14 minutes.

Tobias Harris scored 22 points and Furkan Korkmaz had 21 for the 76ers, who became locked into the No. 6 seed in the Eastern Conference earlier Wednesday, securing a first-round matchup against the Boston Celtics.

In other matches, the Indiana Pacers beat the Houston Rockets 108-104, the Oklahoma City Thunder edged out the Miami Heat 116-115 while the LA Clippers defeated the Denver Nuggets 124-111.