Police are trying to piece together what caused a two-car crash on the notorious Indian Ocean Drive near Lancelin this week, involving five people — three of which had to be rushed to hospital with serious injuries. Police say a grey Honda Accord was travelling south and a grey Isuzu MU-X was travelling north towards Geraldton on Indian Ocean Drive in Karakin on Wednesday when about 3pm they collided near the intersection of Lancelin Road, with passengers on board in both vehicles. The driver of the Honda was a 28-year-old man, with a 26-year old man in the front seat and a 25-year-old rear passenger. A 59-year-old man was driving the Isuzu with a 56-year-old woman in the front passenger seat. A St John WA spokesperson said the 59-year-old man was airlifted to Royal Perth Hospital with serious injuries about 5.54pm. They confirmed the 56-year-old woman and a man in his 20s were taken to Joondalup Hospital by ambulance as priority one patients. “Two had very serious injuries,” they said. The remaining two involved in the incident were treated at the scene. A RPH spokesperson confirmed the 56-year-old was in a stable condition in the State Trauma Unit. Police would like to hear from anyone who saw either vehicle travelling in the area prior to the crash. Anyone with information regarding this crash, or who has dash-cam vision of the crash, is asked to contact Crime Stoppers on 1800 333 000 or online at crimestopperswa.com.au. Last Saturday, a 39-year-old man was flown to RPH with serious injuries after a head-on collision on Brand Highway in Yathroo, north-east of Lancelin.